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OncoMatch/Clinical Trials/NCT07079228

A Study to Compare QLS31905 and Chemotherapy With Placebo and Chemotherapy in Participants With Pancreatic Cancer

Is NCT07079228 recruiting? Yes, currently enrolling (Jun 2026). This Phase 3 trial studies multiple treatments for pancreatic cancer.

Phase 3RecruitingQilu Pharmaceutical Co., Ltd.NCT07079228Data as of Jun 2026Location: China

Treatment: QLS31905 · Nab-paclitaxel. · Gemcitabine · Nab-paclitaxel. · GemcitabineThe goal of this study is to evaluate the efficacy of QLS31905 in combination with chemotherapy (nab-paclitaxel plus gemcitabine \[AG\]) versus placebo in combination with chemotherapy (AG) in the treatment of CLDN18.2-positive advanced pancreatic cancer in adult participants.

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Extracted eligibility criteria

Treatments studied

Chemotherapy

Nab-paclitaxel.GemcitabineNab-paclitaxel.Gemcitabine

Other

QLS31905

Cancer type

Pancreatic Cancer

Performance status

ECOG 0–1(Restricted strenuous activity)

Demographics

Ages ≤ 75

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Lab requirements

Kidney function

adequate renal function

Liver function

adequate liver function

Cardiac function

adequate cardiac function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT07079228 currently recruiting?

Yes, this trial is currently recruiting patients.

Can patients have received prior systemic therapy?

No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.

Is there an age limit?

Yes. Patients must be 75 years or younger.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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