OncoMatch/Clinical Trials/NCT07070219
A Study of CTD402 in T-ALL/LBL Patients
Is NCT07070219 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies CTD402 CAR T Cell for acute lymphocytic leukemia refractory.
Treatment: CTD402 CAR T Cell — The goal of the TENACITY-01 clinical trial is to learn if CTD402 UCART is safe and effective for relapsed/refractory T-ALL/LBL patients. Participants with relapsed/refractory T-ALL/LBL over the age of 12 will be eligible to participate. Participants will receive one infusion of CTD402 on Day 0 and will be evaluated for anti-tumor activity by an independent review committee based on the NCCN criteria for T-ALL and the Lugano 2014 criteria for T-LBL. Patients will be followed for up to 24 months in this study and will be required to enroll under a separate long term follow up protocol to be followed for up to 15 years.
Check if I qualifyExtracted eligibility criteria
Cancer type
Acute Lymphoblastic Leukemia
Non-Hodgkin Lymphoma
Prior therapy
Lab requirements
Blood counts
Kidney function
Liver function
Cardiac function
No history of heart failure NYHA class III or IV; no history of myocardial infarction, cardiovascular angioplasty or stenting, unstable angina, or other serious heart diseases within 12 months of enrollment.
Adequate organ function. Participants with following cardiac conditions will be excluded: History of heart failure New York Heart Association (NYHA) class III or IV; History of myocardial infarction, cardiovascular angioplasty or stenting, unstable angina, or other serious heart diseases within 12 months of enrollment.
Structured fields extracted by AI. May contain errors — verify against the official protocol.
US trial sites
- Stanford University · Palo Alto, California
- Colorado Blood Cancer Institute · Denver, Colorado
- University of Chicago · Chicago, Illinois
- Mayo Clinic - Rochester · Rochester, Minnesota
- Memorial Sloan Kettering Cancer Center · New York, New York
Showing up to 5 US sites. See all sites on ClinicalTrials.gov →
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