OncoMatch/Clinical Trials/NCT07062549
Study of 111In-XYIMSR-01 SPECT/CT in Patients With Metastatic Clear Cell Renal Cell
Is NCT07062549 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies 111In-XYIMSR-01 for renal cell carcinoma (kidney cancer).
Treatment: 111In-XYIMSR-01 — This study is being done to determine if the investigational radiotracer called 111In-XYIMSR-01 is helpful in detecting clear cell renal cell carcinoma tissue in your body when used during a SPECT-CT Scan
Check if I qualifyExtracted eligibility criteria
Cancer type
Renal Cell Carcinoma
Disease stage
Metastatic disease required
Prior therapy
Cannot have received: systemic therapy
Systemic therapy for the treatment of ccRCC within 12 months of study enrollment.
Cannot have received: radioisotope
Subjects administered any radioisotope within five physical half-lives prior to study drug injection.
Lab requirements
Blood counts
Absolute neutrophil count ≥ 1,500 /mm3; Platelets ≥100,000/ mm3; Hemoglobin ≥ 9.0 g/dL; White blood cell count ≥ 2,000/ mm3
Kidney function
Creatinine clearance ≥50 mL/min based on Cockcroft-Gault formula
Liver function
Serum bilirubin ≤ 1.5x ULN (≤ 3x ULN for Gilbert's syndrome); ALT ≤ 3x ULN; AST ≤ 3x ULN
Screening clinical laboratory values as specified below: * Serum bilirubin ≤ 1.5 times the upper limit of normal; for patients with known Gilbert's syndrome, ≤ 3 × ULN is permitted * ALT ≤ 3 times the upper limits of normal * AST ≤ 3 times the upper limits of normal * Creatinine clearance ≥50 mL/min based on Cockcroft-Gault formula * Absolute neutrophil count ≥ 1,500 /mm3 * Platelets ≥100,000/ mm3 * Hemoglobin ≥ 9.0 g/dL * White blood cell count ≥ 2,000/ mm3
Structured fields extracted by AI. May contain errors — verify against the official protocol.
US trial sites
- Johns Hopkins University · Baltimore, Maryland
Showing up to 5 US sites. See all sites on ClinicalTrials.gov →
Could you qualify for this trial?
Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.
Check if I qualify