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OncoMatch/Clinical Trials/NCT07050836

Contrast Enhanced Ultrasound in Neurosurgery to Improve Glioma Visualization and Border Demarcation

Is NCT07050836 recruiting? Yes, currently enrolling (May 2026). This Early Phase 1 trial studies Definity contrast during ultrasound for glioma (any grade) in the brain.

Early Phase 1RecruitingUniversity of Colorado, DenverNCT07050836Data as of May 2026

Treatment: Definity contrast during ultrasoundThis study plans to learn more about using contrast enhanced ultrasound (CEUS) in brain tumor surgery. The goal of glioma brain tumor surgery is to remove as much of the glioma as possible. Tumor tissue that is close to normal brain tissue can look very similar. This can make it difficult for the surgeon to remove all the tumor. In this study, we hope to learn if using CEUS during brain tumor surgery will allow the brain surgeon to better see and remove all the tumor tissue.

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Extracted eligibility criteria

Cancer type

Glioblastoma

Performance status

WHO 0–2

Lab requirements

Cardiac function

known significant cardiac disease, right-to-left shunts, severe pulmonary hypertension (pulmonary artery pressure > 90 mm Hg), uncontrolled systemic hypertension, or adult respiratory distress syndrome [excluded]

Patient with known significant cardiac disease, known to have right-to-left shunts, severe pulmonary hypertension (pulmonary artery pressure > 90 mm Hg), uncontrolled systemic hypertension, or adult respiratory distress syndrome [excluded]

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • University of Colorado Anschutz Medical Campus · Aurora, Colorado

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