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OncoMatch/Clinical Trials/NCT07034326

Electroacupuncture Combined With Immune Checkpoint Inhibitors as Adjuvant Therapy After Surgery for Early-stage Non-small Cell Lung Cancer

Is NCT07034326 recruiting? Yes, currently enrolling (May 2026). This Phase 2/3 trial studies multiple treatments including Zilongjin tablet combined with immunotherapy and Immunotherapy for non-small cell lung cancer.

Phase 2/3RecruitingKong FanmingNCT07034326Data as of May 2026

Treatment: Zilongjin tablet combined with immunotherapy · ImmunotherapyPostoperative immunoadjuvant therapy has been proven to significantly reduce the risk of recurrence after resectable NSCLC, and has become a new standard of postoperative adjuvant therapy for stage II-III NSCLC. Immunotherapy faces challenges such as immune resistance, heterogeneity of biomarker expression, and limitation of immune-suitable population. How to reduce the rate of recurrence and metastasis after surgery, enhance the therapeutic effect of immunotherapy, and then prolong the survival period and improve the quality of life, has become an urgent problem facing the current clinical. Based on the standards of evidence-based medicine, this study for the first time carried out a large sample, multi-center, randomized parallel controlled clinical study to obtain high-quality clinical evidence of the effectiveness and safety of electro-acupuncture and Zilongjin tablet synergic treatment, and formed a standard treatment plan of traditional Chinese medicine.

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Extracted eligibility criteria

Cancer type

Non-Small Cell Lung Carcinoma

Disease stage

Required: Stage Ⅱ, ⅢA, ⅢB (N2)

stage Ⅱ, ⅢA, ⅢB (N2) non-small cell lung cancer diagnosed by pathology or cytology after surgery

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Min 1 prior line

Must have received: chemotherapy — adjuvant

Postoperative adjuvant chemotherapy was received for 1 to 4 cycles

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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