OncoMatch

OncoMatch/Clinical Trials/NCT07024173

A Phase 3 Study of HRS-8080 Versus Treatment Chosen by Physicians in Locally Advanced and Metastatic Breast Cancer

Is NCT07024173 recruiting? Yes, currently enrolling (Jun 2026). This Phase 3 trial studies multiple treatments for locally advanced breast cancer.

Phase 3RecruitingShandong Suncadia Medicine Co., Ltd.NCT07024173Data as of Jun 2026Location: China

Treatment: HRS-8080 Tablet · Fulvestrant · Exemestane tablets · Everolimus Tablets · Anastrozole Tablets · Letrozole TabletsThis study is a multicenter, open-label, randomized controlled Phase 3 clinical trial. It is planned to enroll 240 female patients with locally advanced or metastatic breast cancer followed by disease progression after previous endocrine therapy.

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Extracted eligibility criteria

Treatments studied

Endocrine / hormonal

Fulvestrant

Other

HRS-8080 TabletExemestane tabletsEverolimus TabletsAnastrozole TabletsLetrozole Tablets

Cancer type

Breast Carcinoma

Performance status

ECOG 0–1(Restricted strenuous activity)

Demographics

Ages ≤ 75
Female only

Prior therapy

Max 2 prior lines
Min 1 prior line

Must have received: endocrine therapy

Lab requirements

Blood counts

The functional level of the organs must meet the requirements.

Kidney function

The functional level of the organs must meet the requirements.

Liver function

The functional level of the organs must meet the requirements.

The functional level of the organs must meet the requirements.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT07024173 currently recruiting?

Yes, this trial is currently recruiting patients.

Is prior treatment required for enrollment?

Yes. Patients must have previously received endocrine therapy.

Is there an age limit?

Yes. Patients must be 75 years or younger.

Is this trial open to male patients?

No. This trial enrolls female patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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