OncoMatch/Clinical Trials/NCT07023315
A Phase III Clinical Study of Cadonilimab Plus SOX as Perioperative Treatment for Patients With Resectable G/GEJ Adenocarcinoma
Is NCT07023315 recruiting? Yes, currently enrolling (Jun 2026). This Phase 3 trial studies multiple treatments including Cadonilimab and SOX chemotherapy for gastric and gastroesophageal junction (gej) adenocarcinoma.
Treatment: Cadonilimab · SOX chemotherapy — This study investigates treatment of cadonilimab or placebo combined with SOX chemotherapy (oxaliplatin + tegafur-gimeracil-oteracil potassium) given before surgery (neoadjuvant) and cadonilimab or placebo combined with SOX chemotherapy after surgery (adjuvant), will work and be safe for the treatment of resectable (removable by surgery) gastric or gastroesophageal cancer.
Check if I qualifyExtracted eligibility criteria
Treatments studied
Immunotherapy
Other
Cancer type
Gastric Cancer
Esophageal Carcinoma
Disease stage
Required: Stage T3-4AN+M0, T4BNANYM0 (AJCC 8th edition)
Excluded: Stage UNRESECTABLE LOCALLY ADVANCED DISEASE, DISTANT METASTASIS
clinical stage T3-4aN+M0 or T4bNanyM0 per AJCC 8th edition
Performance status
ECOG 0–1(Restricted strenuous activity)
Demographics
Prior therapy
Cannot have received: anti-cancer therapy
Has received prior anti-cancer therapy for the current malignancy
Lab requirements
Blood counts
Kidney function
Liver function
Has adequate organ function
Structured fields extracted by AI. May contain errors — verify against the official protocol.
Frequently asked questions
Is NCT07023315 currently recruiting?
Yes, this trial is currently recruiting patients.
Can patients have received prior systemic therapy?
No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.
What disease stage is eligible?
Stage T3-4AN+M0 or T4BNANYM0 is required.
Is there an age limit?
Yes. Patients must be 75 years or younger.
Could you qualify for this trial?
Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.
Check if I qualifyRelated pages