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OncoMatch/Clinical Trials/NCT07018050

Phase II Study of QLS32015 Combination Therapy in the Treatment of Multiple Myeloma

Is NCT07018050 recruiting? Yes, currently enrolling (Sep 2026). This Phase 2 trial studies multiple treatments for relapsed or refractory multiple myeloma.

Phase 2RecruitingQilu Pharmaceutical Co., Ltd.NCT07018050Data as of Sep 2026Location: China

Treatment: QLS32015 · Pomalidomide · Dexamethasone · QL2109 or Daratumumab · Bortezomib · LenalidomideThe purpose of the study is to compare the efficacy of QLS32105 (SC) in combination with Pomalidomide, and QLS32105 (SC) in combination with QL2109 or Daratumumab, and QLS32105 (SC) in combination with QL2109 or Daratumumab and Pomalidomide, and QLS32105(SC) in combination with Bortezomib and Lenalidomide.

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Extracted eligibility criteria

Treatments studied

Immunotherapy

QL2109 or Daratumumab

Targeted therapy

Bortezomib

Endocrine / hormonal

PomalidomideLenalidomide

Other

QLS32015Dexamethasone

Cancer type

Multiple Myeloma

Prior therapy

Min 1 prior line

Must have received: anti-multiple myeloma therapy

Cannot have received: gprc5d-targeted therapy

Cannot have received: pomalidomide (pomalidomide)

Exception: applies to treatment cohorts containing pomalidomide

Cannot have received: bortezomib (bortezomib)

Exception: applies to treatment cohorts containing bortezomid

Cannot have received: lenalidomide (lenalidomide)

Exception: applies to treatment cohorts containing lenalidomide

Cannot have received: daratumumab (daratumumab)

Exception: applies to treatment cohorts containing daratumumab

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT07018050 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior gprc5d-targeted therapy, pomalidomide, bortezomib disqualifies patients from enrollment.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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