OncoMatch

OncoMatch/Clinical Trials/NCT07005128

A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carboplatin, and Etoposide in First-line Extensive Stage Small-Cell Lung Cancer (ES-SCLC)

Is NCT07005128 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies multiple treatments including Tarlatamab and Durvalumab for small-cell lung cancer.

Phase 3RecruitingAmgenNCT07005128Data as of May 2026

Treatment: Tarlatamab · Durvalumab · Carboplatin · EtoposideThe main objective of the study is to compare the efficacy of tarlatamab in combination with durvalumab, carboplatin and etoposide to the combination of durvalumab, carboplatin and etoposide on prolonging overall survival (OS).

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Extracted eligibility criteria

Cancer type

Non-Small Cell Lung Carcinoma

Disease stage

Required: Stage IV

Metastatic disease required

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Saint Bernards Medical Center · Jonesboro, Arkansas
  • Translational Research in Oncology US Inc, Trio Central Pharmacy · Los Angeles, California
  • University of California Los Angeles · Santa Monica, California
  • Presbyterian Intercommunity Hospital Health Whitter Hospital · Whittier, California
  • Colorado West Healthcare System dba Grand Valley Oncology · Grand Junction, Colorado

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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