OncoMatch

OncoMatch/Clinical Trials/NCT06984146

Nivo40-AVD for Advanced Classic Hodgkin Lymphoma

Is NCT06984146 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies multiple treatments including Nivolumab and Doxorubicin for hodgkin lymphoma, adult.

Phase 2RecruitingNational Medical Research Radiological Centre of the Ministry of Health of RussiaNCT06984146Data as of Jun 2026Location: Russia

Treatment: Nivolumab · Doxorubicin · Vinblastine · DacarbazineThe aim of the current trial is to evaluate the efficacy and safety of flat-dose nivolumab (40 mg) in combination with AVD in the management of patients with newly diagnosed advanced classic Hodgkin Lymphoma

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Extracted eligibility criteria

Treatments studied

Immunotherapy

Nivolumab

Chemotherapy

DoxorubicinVinblastineDacarbazine

Cancer type

Hodgkin Lymphoma

Disease stage

Required: Stage IIB, III, IV

Performance status

ECOG 0–4(Completely disabled)

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Lab requirements

Kidney function

creatinine <= 2x uln

Liver function

alt or ast <= 5x uln; bilirubin <= 2x uln

Cardiac function

ejection fraction > 50%

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06984146 currently recruiting?

Yes, this trial is currently recruiting patients.

Can patients have received prior systemic therapy?

No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.

What disease stage is eligible?

Stage IIB or III or IV is required.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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