OncoMatch

OncoMatch/Clinical Trials/NCT06983743

A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors

Is NCT06983743 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies multiple treatments including ERAS-0015 and ERAS-0015 in combination for metastatic solid tumors.

Phase 1RecruitingErasca, Inc.NCT06983743Data as of May 2026

Treatment: ERAS-0015 · ERAS-0015 in combinationThe main purpose of the study is to assess whether the study drug, ERAS-0015, is safe and tolerable when administered to patients with advanced or metastatic solid tumors with certain RAS mutations. ERAS-0015 will be given alone or in combination with other treatments.

Check if I qualify

Extracted eligibility criteria

Cancer type

Tumor Agnostic

Disease stage

Required: Stage IV

Metastatic disease required

Advanced or metastatic solid tumors

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Cannot have received: ras inhibitor

Lab requirements

Blood counts

adequate hematological function

Kidney function

adequate renal function

Liver function

adequate liver function

Cardiac function

adequate cardiovascular function

Adequate cardiovascular, hematological, liver, and renal function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Florida Cancer Specalists · Sarasota, Florida
  • Memorial Sloan Kettering Cancer Center · New York, New York
  • The University of Texas MD Anderson Cancer Center · Houston, Texas
  • University of Texas at Tyler · Tyler, Texas
  • NEXT Virginia · Fairfax, Virginia

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

Check if I qualify