OncoMatch/Clinical Trials/NCT06976476
Study of IgPro20 to Prevent Infection in People With Multiple Myeloma and Hypogammaglobulinemia
Is NCT06976476 recruiting? Yes, currently enrolling (Sep 2026). This Phase 2 trial studies IgPro20 for multiple myeloma.
Treatment: IgPro20 — The main purpose of this study is to see if IgPro20 can prevent infection in people with multiple myeloma (MM) who have hypogammaglobulinemia from receiving bispecific monoclonal antibodies (BsAbs).
Check if I qualifyExtracted eligibility criteria
Treatments studied
Other
Cancer type
Multiple Myeloma
Performance status
ECOG 0–3(Limited self-care)
Prior therapy
Must have received: bispecific antibody
Diagnosis of RRMM receiving a commercially available bispecific antibody
Cannot have received: CAR-T cell therapy
Planned CAR-T therapy in the next 6 months
Lab requirements
Blood counts
Neutrophils < 500 x 10^3 per mL, Platelets < 30 x 10^9 per mL [excluded]
Kidney function
Creatinine Cl <30 ml/min [excluded]
Neutrophils < 500 x 10^3 per mL, Platelets < 30 x 10^9 per mL; Creatinine Cl <30 ml/min
Structured fields extracted by AI. May contain errors — verify against the official protocol.
US trial sites
- Memorial Sloan Kettering Basking Ridge (All Protocol Activities) · Basking Ridge, New Jersey
- Memorial Sloan Kettering Monmouth (All Protocol Activities) · Middletown, New Jersey
- Memorial Sloan Kettering Bergen (All Protocol Activities) · Montvale, New Jersey
- Memorial Sloan Kettering Suffolk-Commack (All Protocol Activity) · Commack, New York
- Memorial Sloan Kettering Westchester (All Protocol Activities) · Harrison, New York
Showing up to 5 US sites.
See all sites on ClinicalTrials.gov →Frequently asked questions
Is NCT06976476 currently recruiting?
Yes, this trial is currently recruiting patients.
Are there prior therapy exclusions?
Yes. Prior CAR-T cell therapy disqualifies patients from enrollment.
Could you qualify for this trial?
Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.
Check if I qualifyRelated pages