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OncoMatch/Clinical Trials/NCT06974929

A Clinical Study of HRS-6209 Combined With Other Treatment Regimens in Patients With Breast Cancer

Is NCT06974929 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1/2 trial studies multiple treatments including HRS-6209 Capsules and Letrozole Tablets for breast cancer.

Phase 1/2RecruitingJiangsu HengRui Medicine Co., Ltd.NCT06974929Data as of Jun 2026Location: China

Treatment: HRS-6209 Capsules · Letrozole Tablets · HRS-2189 TabletsThis is a study to evaluate the safety, tolerability, and pharmacokinetic characteristics of HRS-6209 combined with other treatment regimens in breast cancer patients, and preliminarily observe its anti-tumor efficacy.

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Extracted eligibility criteria

Treatments studied

Other

HRS-6209 CapsulesLetrozole TabletsHRS-2189 Tablets

Cancer type

Breast Carcinoma

Performance status

ECOG 0–1(Restricted strenuous activity)

Demographics

Ages ≤ 75
Female only

Prior therapy

Must have received: systemic anti-tumor therapy

Evidence of radiographic disease progression during or after the last systemic anti-tumor therapy prior to the first study drug administration

Cannot have received: surgery

The patients received surgery...within 4 weeks before the first medication

Cannot have received: chemotherapy

The patients received...chemotherapy...within 4 weeks before the first medication

Cannot have received: immunotherapy

The patients received...immunotherapy...within 4 weeks before the first medication

Cannot have received: macromolecular targeted therapy

The patients received...macromolecular targeted therapy within 4 weeks before the first medication

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06974929 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior surgery, chemotherapy, immunotherapy disqualifies patients from enrollment.

Is there an age limit?

Yes. Patients must be 75 years or younger.

Is this trial open to male patients?

No. This trial enrolls female patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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