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OncoMatch/Clinical Trials/NCT06970145

Safety and Efficacy of Anlotinib in the Treatment of Recurrent Craniopharyngioma

Is NCT06970145 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies Anlotinib for craniopharyngiomas.

Phase 1/2RecruitingNanfang Hospital, Southern Medical UniversityNCT06970145Data as of May 2026

Treatment: AnlotinibPrimary Aim: To assess the objective remission rate (ORR) of patients with recurrent craniopharyngiomas treated with anlotinib . Secondary Aims: 1. To assess progression-free survival (PFS) and overall survival (OS) of patients with recurrent craniopharyngiomas treated with anlotinib. 2. To analyze the disease control rate (DCR) of the anlotinib treatment regimen in patients with recurrent craniopharyngiomas, including the proportion of patients in complete remission, partial remission and stable disease. 3. Monitor and evaluate the safety of anlotinib, especially the occurrence of drug-related adverse events (AEs) .

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Extracted eligibility criteria

Prior therapy

Must have received: surgery

recurrence after total resection or regrowth of residual tumor

Cannot have received: same investigational drug

prior treatment with the same investigational drug

Lab requirements

Blood counts

blood tests within the normal range or under control

Kidney function

kidney function within the normal range or under control

Liver function

liver function within the normal range or under control

laboratory parameters (liver and kidney function, blood tests, etc.) within the normal range or under control

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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