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OncoMatch/Clinical Trials/NCT06942104

Imaging of Solid Tumors Using 18F-TRX

Is NCT06942104 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1 trial studies 18F-TRX for solid tumor.

Phase 1RecruitingRahul AggarwalNCT06942104Data as of Jun 2026

Treatment: 18F-TRXThis phase I trial tests the safety and effectiveness of 18F-TRX in detecting tumors (cancer) patients with solid tumors. 18F-TRX is an imaging tracer that is used to visualize tumors using a PET scan. It specifically targets and detects labile (unstable) iron levels within tissues, including tumors. Diagnostic procedures, such as 18F-TRX PET/CT or PET/MRI, may help detect tumors in patients with solid tumors

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Extracted eligibility criteria

Treatments studied

Other

18F-TRX

Cancer type

Tumor Agnostic

Prostate Cancer

Renal Cell Carcinoma

Glioblastoma

Disease stage

Required: Stage III, IV, STAGE III RENAL CELL CANCER AJCC V8, STAGE IV RENAL CELL CANCER AJCC V8, STAGE IVB PROSTATE CANCER AJCC V8 (AJCC v8)

Grade: WHO grade 3WHO grade 4 (WHO)

Advanced solid tumor malignancy in one of the following cohorts: ... WHO grade 3 or 4 glioma ... Locally advanced or metastatic clear cell renal cell carcinoma ... Metastatic castration-resistant prostate cancer ... Stage III Renal Cell Cancer AJCC v8; Stage IV Renal Cell Cancer AJCC v8; Stage IVB Prostate Cancer AJCC v8

Performance status

ECOG 0–1(Restricted strenuous activity)

Lab requirements

Blood counts

Absolute neutrophil count > 1.5 x 10^6/L; Platelets > 75,000 x 10^6/L; Hemoglobin > 8 g/dL

Kidney function

Creatinine clearance > 50 ml/min, calculated using the Cockcroft-Gault equation

Liver function

Total bilirubin < 1.5 x upper limit of normal; AST < 2.5 x ULN (< 5 x ULN with liver metastases); ALT < 2.5 x ULN (< 5 x ULN with liver metastases)

Absolute neutrophil count > 1.5 x 10^6/L; Platelets > 75,000 x 10^6/L; Hemoglobin > 8 g/dL; Total bilirubin < 1.5 x upper limit of normal; AST < 2.5 x ULN (< 5 x ULN with liver metastases); ALT < 2.5 x ULN (< 5 x ULN with liver metastases); Creatinine clearance > 50 ml/min, calculated using the Cockcroft-Gault equation.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • University of California, San Francisco · San Francisco, California

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT06942104 currently recruiting?

Yes, this trial is currently recruiting patients.

What disease stage is eligible?

Stage III or IV or STAGE III RENAL CELL CANCER AJCC V8 or STAGE IV RENAL CELL CANCER AJCC V8 or STAGE IVB PROSTATE CANCER AJCC V8 is required.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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