OncoMatch/Clinical Trials/NCT06941857
NC410 and FOLFIRINOX in Combination With Nivolumab With or Without Ipilimumab in Patients With Untreated Metastatic Pancreatic Cancer
Is NCT06941857 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies multiple treatments for pancreatic cancer.
Treatment: Oxaliplatin · Irinotecan · Folinic Acid · 5-Fluorouracil (5-FU) · NC410 · Nivolumab · Ipilimumab — The purpose of this study is to evaluate safety of the treatment regimen and identify any novel toxicities.
Check if I qualifyExtracted eligibility criteria
Cancer type
Pancreatic Cancer
Disease stage
Metastatic disease required
Performance status
ECOG 0–1(Restricted strenuous activity)
Prior therapy
Cannot have received: chemotherapy
Have had prior chemotherapy for pancreatic cancer or prior chemotherapy within 5 years of enrollment for other cancer diagnoses.
Cannot have received: radiation therapy
Has received radiotherapy for pancreatic cancer.
Cannot have received: anti-PD-1 therapy
Has received prior therapy with an anti-PD-1, anti-PD-L1, anti-PD-L2, anti-CTLA4, or anti-Lag-3 antibodies.
Cannot have received: investigational agent
Are receiving or have received any investigational agent or used an investigational device within 28 days prior to Day 1 of treatment in this study.
Lab requirements
Blood counts
adequate organ and marrow function defined by study-specified laboratory tests and procedures
Kidney function
adequate organ and marrow function defined by study-specified laboratory tests and procedures
Liver function
adequate organ and marrow function defined by study-specified laboratory tests and procedures
Structured fields extracted by AI. May contain errors — verify against the official protocol.
US trial sites
- Sidney Kimmel Comprehensive Cancer Center · Baltimore, Maryland
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