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OncoMatch/Clinical Trials/NCT06932562

A Study to Learn How Safe and How Well Linvoseltamab Works Compared to Standard Treatment in Adult Patients With Multiple Myeloma Who Are Not Eligible for Transplant

Is NCT06932562 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies multiple treatments including Linvoseltamab and Daratumumab for multiple myeloma.

Phase 3RecruitingEuropean Myeloma Network B.V.NCT06932562Data as of May 2026

Treatment: Linvoseltamab · Daratumumab · Lenalidomide · DexamethasoneThis study is researching an experimental drug called linvoseltamab. The study is focused on participants with newly diagnosed multiple myeloma (NDMM) who are ineligible for autologous stem cell transplantation (transplant-ineligible). The main purpose of this study is to compare the effect and safety of linvoseltamab with the effect and safety of the standard treatment.

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Extracted eligibility criteria

Cancer type

Multiple Myeloma

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: any prior therapy for MGUS, SMM, or MM

Exception: focal radiation and/or a short course of corticosteroids as defined in the protocol

Any prior therapy for monoclonal gammopathy of undetermined significance (MGUS), smoldering multiple myeloma (SMM), or MM, with the exception of: focal radiation and/or a short course of corticosteroids as defined in the protocol.

Cannot have received: investigational agent or cell therapy with known or suspected activity against MM

Participants who have received or are receiving any investigational agent or cell therapy with known or suspected activity against MM

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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