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OncoMatch/Clinical Trials/NCT06932471

Study of Safety and Efficacy of MY008211A in Patients With Residual Anemia Despite Anti-C5 Antibody Treatment

Is NCT06932471 recruiting? Yes, currently enrolling (Jun 2026). This Phase 3 trial studies MY008211A tablets for paroxysmal nocturnal hemoglobinuria.

Phase 3RecruitingWuhan Createrna Science and Technology Co., LtdNCT06932471Data as of Jun 2026Location: China

Treatment: MY008211A tabletsThe main purpose of this study is to evaluate the efficacy of MY008211A in PNH patients with residual anemia despite treatment with anti-C5 antibody.

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Extracted eligibility criteria

Treatments studied

Other

MY008211A tablets

Demographics

Ages ≤ 75

Prior therapy

Must have received: anti-C5 antibody

Stable regimen of anti-C5 antibody treatment for at least 6 months before treatment

Cannot have received: bone marrow or hematopoietic stem cell transplantation

Previous bone marrow or hematopoietic stem cell transplantation

Cannot have received: splenectomy

Previous splenectomy

Lab requirements

Blood counts

reticulocytes ≥100x10^9/l; platelets ≥30x10^9/l; neutrophils ≥0.5x10^9/l

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06932471 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior bone marrow or hematopoietic stem cell transplantation, splenectomy disqualifies patients from enrollment.

Is there an age limit?

Yes. Patients must be 75 years or younger.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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