OncoMatch

OncoMatch/Clinical Trials/NCT06922539

ST-001 nanoFenretinide in Relapsed/ Refractory Small Cell Lung Cancer

Is NCT06922539 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies multiple treatments including Fenretinide and Fenretinide for small cell lung cancer.

Phase 1RecruitingSciTech Development, Inc.NCT06922539Data as of May 2026

Treatment: Fenretinide · FenretinideThis study evaluates a fenretinide phospholipid suspension for the treatment of small cell lung cancer (SCLC).

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Extracted eligibility criteria

Cancer type

Small Cell Lung Cancer

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Min 1 prior line

Must have received: platinum-based chemotherapy

Patients must have had prior treatment with radiation therapy or with platinum-based chemotherapy ± immunotherapy with no limit on the number of prior systemic treatment regimens.

Must have received: radiation therapy

Patients must have had prior treatment with radiation therapy or with platinum-based chemotherapy ± immunotherapy with no limit on the number of prior systemic treatment regimens.

Cannot have received: chemotherapy or radiotherapy (nitrosoureas, mitomycin C)

Exception: allowed if completed ≥4 weeks prior (≥6 weeks for nitrosoureas or mitomycin C) and recovered from toxicity

Patients who have had chemotherapy or radiotherapy within 4 weeks (6 weeks for nitrosoureas or mitomycin C) prior to entering the study or those who have not recovered from adverse events due to agents administered more than 4 weeks earlier.

Lab requirements

Blood counts

normal organ and marrow function

Kidney function

normal organ and marrow function

Liver function

normal organ and marrow function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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