OncoMatch

OncoMatch/Clinical Trials/NCT06906341

Relacorilant in Combination With Different Treatment Regimens in Patients With Gynecological Cancers

Is NCT06906341 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies multiple treatments including Relacorilant 150 mg once daily (QD) and Nab-paclitaxel 80 mg/m^2 for ovarian cancer.

Phase 2RecruitingCorcept TherapeuticsNCT06906341Data as of Jun 2026Location: International · 8 countries

Treatment: Relacorilant 150 mg once daily (QD) · Nab-paclitaxel 80 mg/m^2 · Bevacizumab 10 mg/kgThis is a Phase 2, open-label, global, multi-arm study to evaluate efficacy and safety of relacorilant in combination with other treatments in patients with gynecological cancers.

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Extracted eligibility criteria

Treatments studied

Targeted therapy

Bevacizumab 10 mg/kg

Chemotherapy

Nab-paclitaxel 80 mg/m^2

Other

Relacorilant 150 mg once daily (QD)

Cancer type

Ovarian Cancer

Endometrial Cancer

Disease stage

Required: Stage III, IV

Performance status

ECOG 0–1(Restricted strenuous activity)

Demographics

Female only

Prior therapy

Must have received: systemic anticancer therapy

1 to 3 lines of prior systemic anticancer therapy

Must have received: systemic anticancer therapy — endometrial cancer

1 to 2 lines of prior systemic anticancer therapy for endometrial cancer

Must have received: platinum-based chemotherapy — endometrial cancer

Prior treatment with a platinum agent

Must have received: anti-PD-L1 therapy — endometrial cancer

Prior treatment with an approved anti-Programmed Cell Death Ligand 1 (PD[L]1) antibody

Cannot have received: relacorilant

Prior enrollment in a clinical trial of relacorilant

Cannot have received: weekly paclitaxel or nab-paclitaxel (paclitaxel, nab-paclitaxel)

Has progressed while receiving weekly paclitaxel or nab-paclitaxel

Lab requirements

Blood counts

Kidney function

Liver function

Adequate organ function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • 150 · Palo Alto, California
  • 014 · San Francisco, California
  • 544 · Fort Myers, Florida
  • 543 · West Palm Beach, Florida
  • 518 · Minneapolis, Minnesota

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT06906341 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior relacorilant, weekly paclitaxel or nab-paclitaxel disqualifies patients from enrollment.

What disease stage is eligible?

Stage III or IV is required.

Is this trial open to male patients?

No. This trial enrolls female patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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