OncoMatch

OncoMatch/Clinical Trials/NCT06900647

Bortezomib Plus Cisplatin in Recurrent or Metastatic Breast Cancer

Is NCT06900647 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1 trial studies multiple treatments for metastatic breast cancer.

Phase 1RecruitingSun Yat-sen UniversityNCT06900647Data as of Jun 2026Location: China

Treatment: Bortezomib (B) · Cisplatin (CDDP) · Bortezomib (B) · Bortezomib (B) · Cisplatin (CDDP)This a phase 1 study to evaluate the safety and preliminary efficacy of cisplatin combined with bortezomib in patients with recurrent or metastatic breast cancer.

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Extracted eligibility criteria

Treatments studied

Chemotherapy

Cisplatin (CDDP)Cisplatin (CDDP)

Other

Bortezomib (B)Bortezomib (B)Bortezomib (B)

Cancer type

Breast Carcinoma

Disease stage

Metastatic disease required

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Demographics

Female only

Lab requirements

Blood counts

anc ≥1.5×109/l, plt ≥75×109/l, hb ≥85g/l (no blood transfusion and blood products within 14 days, no use of g-csf and other hematopoietic stimulating factors for correction)

Kidney function

bun and cr ≤1×uln or endogenous creatinine clearance ≥50ml/min (cockcroft-gault formula)

Liver function

tbil <1.5×uln, alt, ast <2.5×uln, alt, ast <5×uln for patients with liver metastasis

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06900647 currently recruiting?

Yes, this trial is currently recruiting patients.

Is this trial open to male patients?

No. This trial enrolls female patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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