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OncoMatch/Clinical Trials/NCT06895031

Study of JYP0015 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

Is NCT06895031 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies JYP0015 for solid tumor.

Phase 2RecruitingGuangzhou JOYO Pharma Co., LtdNCT06895031Data as of May 2026

Treatment: JYP0015Evaluate the safety and antitumor activity of JYP0015 in adults with specific RAS mutant advanced solid tumors.

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Extracted eligibility criteria

Cancer type

Tumor Agnostic

Pancreatic Cancer

Non-Small Cell Lung Carcinoma

Colorectal Cancer

Biomarker criteria

Required: HRAS mutation

Required: KRAS mutation

Required: NRAS mutation

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Must have received: adequate standard treatment

Patients with RAS mutation who have disease progression or intolerance after adequate standard treatment

Lab requirements

Blood counts

Kidney function

Liver function

Adequate organ function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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