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OncoMatch/Clinical Trials/NCT06881992

A Phase 3 Study of Ersodetug in Patients With Tumor Hyperinsulinism

Is NCT06881992 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies Ersodetug for tumor hyperinsulinism (tumor hi).

Phase 3RecruitingRezoluteNCT06881992Data as of May 2026

Treatment: ErsodetugThe objectives of this study are to evaluate the glycemic efficacy, safety, and tolerability of ersodetug as add-on to standard of care (SOC) therapy for treatment of hypoglycemia in patients with Tumor Hyperinsulinism (Tumor HI).

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Extracted eligibility criteria

Prior therapy

Must have received: anti-hypoglycemic therapy

failed to achieve adequate control of hypoglycemia with usual SOC anti-hypoglycemic therapies

Cannot have received: investigational drug or device

Exception: if the treating physician and Medical Monitor consider no significant risk of drug-drug interaction and potential benefit outweighs the risk then the participant may be allowed

Treatment with an investigational drug or device within 30 days or 5 half-lives of the investigational drug (whichever is longer)

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Investigative Site · Chicago, Illinois
  • Investigative Site · Bethesda, Maryland
  • Investigative Site · Boston, Massachusetts
  • Investigative Site · Rochester, Minnesota
  • Investigative Site · New York, New York

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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