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OncoMatch/Clinical Trials/NCT06876662

A Study of (LY3527727) Pirtobrutinib in Participants With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin Lymphoma

Is NCT06876662 recruiting? Yes, currently enrolling (Jun 2026). This Phase 4 trial studies Pirtobrutinib for chronic lymphocytic leukemia.

Phase 4RecruitingEli Lilly and CompanyNCT06876662Data as of Jun 2026Location: International · 8 countries

Treatment: PirtobrutinibStudy J2N-MC-JZ01 (JZ01) is an individual-study appendix (ISA) under master protocol J2N-MC-JZNY, and represents participants from the completed originator study, clinical study LOXO-BTK-18001/J2N-OX-JZNA. Participants in the originator study will have the opportunity to continue their assigned study intervention or continue their follow-up visits by transitioning to this study. This study will evaluate the long-term safety and efficacy of pirtobrutinib.

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Extracted eligibility criteria

Treatments studied

Targeted therapy

Pirtobrutinib

Cancer type

Chronic Lymphocytic Leukemia

Non-Hodgkin Lymphoma

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Sylvester Comprehensive Cancer Center · Miami, Florida
  • Florida Cancer Specialists · Sarasota, Florida
  • The Emory Clinic · Atlanta, Georgia
  • Northwestern University · Chicago, Illinois
  • Dana-Farber Cancer Institute · Boston, Massachusetts

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Frequently asked questions

Is NCT06876662 currently recruiting?

Yes, this trial is currently recruiting patients.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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