OncoMatch/Clinical Trials/NCT06856447
The Role of Coenzyme Q10 in the Prophylaxis of Oxaliplatin Induced Peripheral Neuropathy in Patients With Colorectal Cancer
Is NCT06856447 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1 trial studies multiple treatments for colorectal cancer.
Treatment: Coenzyme Q10 · Oxaliplatin · 5-Fluorouracil (5-FU) · 5-HT3 Antagonist · Pantoprazole — This study aims to evaluate the possible beneficial role of coenzyme Q10 against oxaliplatin-induced peripheral neuropathy in patients with colorectal cancer.
Check if I qualifyExtracted eligibility criteria
Treatments studied
Chemotherapy
Other
Cancer type
Colorectal Cancer
Disease stage
Required: Stage III
Performance status
ECOG 0–1(Restricted strenuous activity)
Prior therapy
Cannot have received: neurotoxic agent (cisplatin, vincristine, paclitaxel, docetaxol, foscarnet, INH)
Patients with prior exposure to neurotoxic agents (Cisplatin, vincristine, paclitaxel, docetaxol, foscarnet, INH, etc..) in the last 6 months.
Lab requirements
Blood counts
absolute neutrophilic count ≥ 1.5 × 10^9 /L, platelet count ≥ 100 × 10^9 /L and hemoglobin level ≥ 10 g/dl
Kidney function
serum creatinine < 1.5 mg/dl
Liver function
serum bilirubin < 1.2 mg/dl
Adequate baseline hematologic values (absolute neutrophilic count ≥ 1.5 × 10^9 /L, platelet count ≥ 100 × 10^9 /L and hemoglobin level ≥ 10 g/dl). Patients with adequate renal function (serum creatinine < 1.5 mg/dl). Patients with adequate liver function (serum bilirubin < 1.2 mg/dl).
Structured fields extracted by AI. May contain errors — verify against the official protocol.
Frequently asked questions
Is NCT06856447 currently recruiting?
Yes, this trial is currently recruiting patients.
Are there prior therapy exclusions?
Yes. Prior neurotoxic agent disqualifies patients from enrollment.
What disease stage is eligible?
Stage III is required.
Could you qualify for this trial?
Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.
Check if I qualifyRelated pages