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OncoMatch/Clinical Trials/NCT06856187

Second-line Standard Treatment Sequential TAS-102 and Bevacizumab Combined With Local Treatment in Advanced Colorectal Cancer

Is NCT06856187 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies multiple treatments including TAS-102+bevacizumab+local treatment and Standard chemotherapy for metastatic colorectal cancer (crc).

Phase 2RecruitingFudan UniversityNCT06856187Data as of May 2026

Treatment: TAS-102+bevacizumab+local treatment · Standard chemotherapyThis study is a randomized, controlled, open-label, phase II clinical study. This study is designed to evaluate the efficacy and safety of second-line standard treatment sequential TAS-102 and bevacizumab combined with local treatment versus continuous treatment of standard second-line therapy in advanced colorectal cancer.

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Extracted eligibility criteria

Cancer type

Colorectal Cancer

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Min 1 prior line

Must have received: first-line standard therapy

Patients who have failed first-line standard therapy and are intended to receive second-line standard therapy

Cannot have received: TAS-102 (TAS-102)

Prior treatment with TAS-102

Lab requirements

Blood counts

Adequate major organ function

Kidney function

Adequate major organ function

Liver function

Adequate major organ function

Adequate major organ function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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