OncoMatch/Clinical Trials/NCT06855069
HS-20089 for Injection in Patients With Platinum-Resistant Recurrent Epithelial Ovarian Cancer
Is NCT06855069 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies multiple treatments including HS-20089 and Paclitaxel for ovarian cancer.
Treatment: HS-20089 · Paclitaxel · Doxorubicin · Topotecan — This study is a randomized, open-label, controlled, phase III study to evaluate the efficacy and safety of HS-20089 versus investigator's choice of chemotherapy in patients with platinum-resistant recurrent epithelial ovarian cancer.
Check if I qualifyExtracted eligibility criteria
Cancer type
Ovarian Cancer
Performance status
ECOG 0–1(Restricted strenuous activity)
Prior therapy
Must have received: platinum-based chemotherapy
Patients must have platinum-resistant disease
Cannot have received: TOP1 inhibitor
Prior treated with TOP1 inhibitors
Cannot have received: antibody-drug conjugate
Exception: if payload is TOP1 inhibitor
ADCs with TOP1 inhibitors as payload
Lab requirements
Blood counts
adequate bone marrow reserve
Kidney function
adequate organ function
Liver function
adequate organ function
Adequate bone marrow reserve and organ function.
Structured fields extracted by AI. May contain errors — verify against the official protocol.
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