OncoMatch/Clinical Trials/NCT06807606
Optimized Cord Blood Transplantation for the Treatment of Patients With High-risk Hematologic Malignancies Who Have Relapsed After First Allogeneic Stem Cell Transplantation
Is NCT06807606 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies multiple treatments for hematologic malignancies.
Treatment: Drugs Cyclophosphamide · Fludarabine · Thiotepa · Tacrolimus · Mycophenolate mofetil — The goal of this clinical research study is to learn if intermediate-intensity conditioning therapy followed by a cord blood transplant can help to control high-risk hematological malignancies in patients who need a second allogeneic stem cell transplantation.
Check if I qualifyExtracted eligibility criteria
Treatments studied
Chemotherapy
Other
Cancer type
Acute Myeloid Leukemia
Acute Lymphoblastic Leukemia
Non-Hodgkin Lymphoma
Multiple Myeloma
Myelodysplastic Syndrome
Chronic Lymphocytic Leukemia
Demographics
Prior therapy
Must have received: stem cell transplant — allogeneic
Lab requirements
Kidney function
Calculated creatinine clearance > 50 ml/min
Liver function
Bilirubin < 2 mg/dL (unless benign congenital hyperbilirubinemia or hemolysis); ALT < 5 x upper limit of normal (ULN)
Cardiac function
Left ventricular ejection fraction (MOD-bp) > 50%
Calculated creatinine clearance > 50 ml/min. Bilirubin < 2 mg/dL (unless benign congenital hyperbilirubinemia or hemolysis). ALT < 5 x upper limit of normal (ULN). Left ventricular ejection fraction (MOD-bp) > 50%.
Structured fields extracted by AI. May contain errors — verify against the official protocol.
US trial sites
- The University of Texas M. D. Anderson Cancer Center · Houston, Texas
Showing up to 5 US sites.
See all sites on ClinicalTrials.gov →Frequently asked questions
Is NCT06807606 currently recruiting?
Yes, this trial is currently recruiting patients.
Is prior treatment required for enrollment?
Yes. Patients must have previously received stem cell transplant.
Is there an age limit?
Yes. Patients must be 60 years or younger and at least 0 years old.
Could you qualify for this trial?
Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.
Check if I qualify