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OncoMatch/Clinical Trials/NCT06801236

Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant Prostate Cancer

Is NCT06801236 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies ACE-232 tablets for prostate cancer (adenocarcinoma).

Phase 1RecruitingAcerand Therapeutics (Hong Kong) LimitedNCT06801236Data as of May 2026

Treatment: ACE-232 tabletsThis is an open label, phase I, multi-center study aiming to assess the safety and tolerability in patients with metastatic castration resistant prostate cancer (mCRPC).

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Extracted eligibility criteria

Cancer type

Prostate Cancer

Disease stage

Metastatic disease required

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Min 2 prior lines

Must have received: novel hormonal agent — mHSPC or mCRPC

post at least 1 line of NHA

Must have received: taxane — mHSPC or mCRPC

post at least 1 line of ... taxane-based chemo

Lab requirements

Blood counts

adequate bone marrow function

Kidney function

adequate organ function

Liver function

adequate organ function

Adequate organ function and bone marrow function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • University of California San Diego, Moores Cancer Center · La Jolla, California
  • Moffitt Cancer Center, Tampa · Tampa, Florida
  • University of Maryland, Greenebaum Comprehensive Cancer Center · Baltimore, Maryland
  • Harvard Medical School-Massachusetts General Hospital · Boston, Massachusetts
  • M Health Fairview Clinics and Surgery Center · Minneapolis, Minnesota

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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