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OncoMatch/Clinical Trials/NCT06797999

First-in-Human Study of ADCE-D01 in Soft Tissue Sarcoma

Is NCT06797999 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies Antibody-drug conjugate (ADC) for metastatic soft tissue sarcoma.

Phase 1/2RecruitingAdcendo ApSNCT06797999Data as of May 2026

Treatment: Antibody-drug conjugate (ADC)The goal of this clinical trial is to learn about the safety, tolerability and efficacy of ADCE-D01.

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Extracted eligibility criteria

Cancer type

Sarcoma

Disease stage

Metastatic disease required

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Max 2 prior lines
Min 1 prior line

Must have received: cytotoxic chemotherapy — metastatic/unresectable

Prior treatment with at least one but no more than two lines of cytotoxic systemic therapy for metastatic/unresectable disease

Cannot have received: systemic anticancer therapy

Patients who have had systemic anticancer therapy, including any investigational agent within 4 weeks or 5 half-lives (whichever is shorter) prior to study treatment administration

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • University of Colorado Denver · Aurora, Colorado
  • University of Miami - Sylvester Comprehensive Cancer Center · Miami, Florida
  • Memorial Sloan Kettering Cancer Center · New York, New York
  • University Of Texas MD Anderson Cancer Center · Houston, Texas

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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