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OncoMatch/Clinical Trials/NCT06797999

First-in-Human Study of ADCE-D01 in Soft Tissue Sarcoma

Is NCT06797999 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1/2 trial studies Antibody-drug conjugate (ADC) for metastatic soft tissue sarcoma.

Phase 1/2RecruitingAdcendo ApSNCT06797999Data as of Jun 2026Location: International · 5 countries

Treatment: Antibody-drug conjugate (ADC)The goal of this clinical trial is to learn about the safety, tolerability and efficacy of ADCE-D01.

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Extracted eligibility criteria

Treatments studied

Other

Antibody-drug conjugate (ADC)

Cancer type

Sarcoma

Disease stage

Metastatic disease required

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Max 2 prior lines
Min 1 prior line

Must have received: cytotoxic chemotherapy — metastatic/unresectable

Prior treatment with at least one but no more than two lines of cytotoxic systemic therapy for metastatic/unresectable disease

Cannot have received: systemic anticancer therapy

Patients who have had systemic anticancer therapy, including any investigational agent within 4 weeks or 5 half-lives (whichever is shorter) prior to study treatment administration

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • University of Colorado Denver · Aurora, Colorado
  • University of Miami - Sylvester Comprehensive Cancer Center · Miami, Florida
  • Memorial Sloan Kettering Cancer Center · New York, New York
  • University Of Texas MD Anderson Cancer Center · Houston, Texas

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT06797999 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior systemic anticancer therapy disqualifies patients from enrollment.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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Related pages

Sarcoma trials