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OncoMatch/Clinical Trials/NCT06793449

BCMA CAR-T Versus ASCT in Transplant-eligible Patients With Multiple Myeloma

Is NCT06793449 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies multiple treatments including anti-BCMA CAR-T and ASCT for multiple myeloma.

Phase 2RecruitingInstitute of Hematology & Blood Diseases Hospital, ChinaNCT06793449Data as of May 2026

Treatment: anti-BCMA CAR-T · ASCTThis is a prospective, non-inferiority study comparing VRD±D followed by BCMA CAR-T cell therapy versus VRD±D followed by autologous hematopoietic stem cell transplantation in the treatment of newly diagnosed multiple myeloma patients.

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Extracted eligibility criteria

Cancer type

Multiple Myeloma

Biomarker criteria

Required: BCMA (TNFRSF17) expression (confirmed expression of the BCMA target antigen on MM cells)

Confirmed expression of the BCMA target antigen on MM cells by flow cytometry or bone marrow immunohistochemistry

Prior therapy

Cannot have received: bcma-targeted therapy

Cannot have received: car-t cell therapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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