OncoMatch

OncoMatch/Clinical Trials/NCT06783829

A Study of SHR-4394 Injection in Subjects With Prostate Cancer

Is NCT06783829 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1 trial studies SHR4394 for prostate cancer.

Phase 1RecruitingJiangsu HengRui Medicine Co., Ltd.NCT06783829Data as of Jun 2026Location: China

Treatment: SHR4394This is an open label, multi-center, multiple dose Phase I study to evaluate the safety, tolerability, pharmacokinetics and efficacy of SHR-4394 injection in subjects with prostate cancer.

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Extracted eligibility criteria

Treatments studied

Other

SHR4394

Cancer type

Prostate Cancer

Disease stage

Metastatic disease required

Performance status

ECOG 0–1(Restricted strenuous activity)

Demographics

Ages ≤ 85
Male only

Prior therapy

Min 1 prior line

Must have received: luteinizing hormone releasing hormone analogue or bilateral orchidectomy

Continuous treatment with luteinizing hormone releasing hormone analogues (LHRHa) or previous bilateral orchidectomy

Cannot have received: systemic anticancer treatments or clinical investigational drugs

Exception: within 4 weeks prior to the initiation of the study treatment

Received systemic anticancer treatments or clinical investigational drugs 4 weeks prior to the initiation of the study treatment

Lab requirements

Blood counts

Kidney function

Liver function

Adequate organ function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06783829 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior systemic anticancer treatments or clinical investigational drugs disqualifies patients from enrollment.

Is there an age limit?

Yes. Patients must be 85 years or younger.

Is this trial open to female patients?

No. This trial enrolls male patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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