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OncoMatch/Clinical Trials/NCT06783829

A Study of SHR-4394 Injection in Subjects With Prostate Cancer

Is NCT06783829 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies SHR4394 for prostate cancer.

Phase 1RecruitingJiangsu HengRui Medicine Co., Ltd.NCT06783829Data as of May 2026

Treatment: SHR4394This is an open label, multi-center, multiple dose Phase I study to evaluate the safety, tolerability, pharmacokinetics and efficacy of SHR-4394 injection in subjects with prostate cancer.

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Extracted eligibility criteria

Cancer type

Prostate Cancer

Disease stage

Metastatic disease required

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Min 1 prior line

Must have received: luteinizing hormone releasing hormone analogue or bilateral orchidectomy

Continuous treatment with luteinizing hormone releasing hormone analogues (LHRHa) or previous bilateral orchidectomy

Cannot have received: systemic anticancer treatments or clinical investigational drugs

Exception: within 4 weeks prior to the initiation of the study treatment

Received systemic anticancer treatments or clinical investigational drugs 4 weeks prior to the initiation of the study treatment

Lab requirements

Blood counts

Kidney function

Liver function

Adequate organ function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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