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OncoMatch/Clinical Trials/NCT06771518

Association of Thoraco-mediastinal Radiotherapy With Maintenance Immunotherapy Treatment With Atezolizumab

Is NCT06771518 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies Atezolizumab 1200 mg e.v. q21 for small cell lung cancer.

Phase 2RecruitingRegina Elena Cancer InstituteNCT06771518Data as of May 2026

Treatment: Atezolizumab 1200 mg e.v. q21Investigate the role of consolidative radiotherapy treatment at the thoraco-mediastinal level in the patient suffering from lung microcytoma - extensive disease and treated with chemo-immunotherapy with atezolizumab, in association with maintenance therapy with atezolizumab.

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Extracted eligibility criteria

Cancer type

Small Cell Lung Cancer

Disease stage

Required: Stage EXTENDED DISEASE

Extended disease at the time of first line oncological treatment

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Min 1 prior line

Must have received: chemoimmunotherapy — first line

chemoimmunotherapy according to the Impower 133 scheme

Cannot have received: radiation therapy

Exception: thoraco-mediastinal level only

Previous radiotherapy treatment at the thoraco-mediastinal level

Lab requirements

Blood counts

Haematological toxicity ≤ G1

Haematological, respiratory toxicity ≤ G1, other toxicities ≤ G2 at the time of treatment radiotherapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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