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OncoMatch/Clinical Trials/NCT06771518

Association of Thoraco-mediastinal Radiotherapy With Maintenance Immunotherapy Treatment With Atezolizumab

Is NCT06771518 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies Atezolizumab 1200 mg e.v. q21 for small cell lung cancer.

Phase 2RecruitingRegina Elena Cancer InstituteNCT06771518Data as of Jun 2026Location: Italy

Treatment: Atezolizumab 1200 mg e.v. q21Investigate the role of consolidative radiotherapy treatment at the thoraco-mediastinal level in the patient suffering from lung microcytoma - extensive disease and treated with chemo-immunotherapy with atezolizumab, in association with maintenance therapy with atezolizumab.

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Extracted eligibility criteria

Treatments studied

Immunotherapy

Atezolizumab 1200 mg e.v. q21

Cancer type

Small Cell Lung Cancer

Disease stage

Required: Stage EXTENDED DISEASE

Extended disease at the time of first line oncological treatment

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Min 1 prior line

Must have received: chemoimmunotherapy — first line

chemoimmunotherapy according to the Impower 133 scheme

Cannot have received: radiation therapy

Exception: thoraco-mediastinal level only

Previous radiotherapy treatment at the thoraco-mediastinal level

Lab requirements

Blood counts

Haematological toxicity ≤ G1

Haematological, respiratory toxicity ≤ G1, other toxicities ≤ G2 at the time of treatment radiotherapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06771518 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior radiation therapy disqualifies patients from enrollment.

What disease stage is eligible?

Stage EXTENDED DISEASE is required.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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