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OncoMatch/Clinical Trials/NCT06771219

SLV-154 Treatment of Metastatic Solid Tumors

Is NCT06771219 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies SLV-154 for squamous cell cancer of head and neck (scchn).

Phase 1RecruitingSolve TherapeuticsNCT06771219Data as of May 2026

Treatment: SLV-154This is a Phase 1 dose-escalation study evaluating the safety, pharmacokinetics, pharmacodynamics, immunogenicity, and efficacy of SLV-154 across a range of dose levels when administered to subjects with metastatic solid tumors.

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Extracted eligibility criteria

Cancer type

Non-Small Cell Lung Carcinoma

Small Cell Lung Cancer

Cervical Cancer

Breast Carcinoma

Endometrial Cancer

Ovarian Cancer

Urothelial Carcinoma

Sarcoma

Thyroid Cancer

Disease stage

Metastatic disease required

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Min 1 prior line

Must have received: commercially available therapies indicated for the subject's cancer and have demonstrated survival benefit

Prior receipt of commercially available therapies that are indicated for the subject's cancer and have demonstrated survival benefit for that indication

Lab requirements

Blood counts

adequate hematological profile

Kidney function

adequate renal function

Liver function

adequate hepatic profile

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Hoag Memorial Hospital Presbyterian · Newport Beach, California
  • Washington University · St Louis, Missouri
  • Astera Cancer Care · East Brunswick, New Jersey
  • Memorial Sloan Kettering Cancer Center · New York, New York
  • MD Anderson Cancer Center · Houston, Texas

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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