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OncoMatch/Clinical Trials/NCT06758544

A Single-arm, Open-label Clinical Study to Evaluate the Efficacy and Safety of VRT106 in Combination With Chemotherapy for Resectable Pancreatic Cancer

Is NCT06758544 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies multiple treatments including Oncolytic virus VRT106 and Chemotherapy for pancreatic cancer.

Phase 1/2RecruitingGuangdong Provincial People's HospitalNCT06758544Data as of May 2026

Treatment: Oncolytic virus VRT106 · ChemotherapyThis is a single-center, single-arm, open investigator-initiated clinical study to evaluate the efficacy and safety of VRT106 in combination with chemotherapy in the treatment of resectable pancreatic cancer.

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Extracted eligibility criteria

Cancer type

Pancreatic Cancer

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: oncolytic virus

Prior treatment with other oncolytic virus or systemic therapy for pancreatic cancer

Cannot have received: systemic therapy

Prior treatment with other oncolytic virus or systemic therapy for pancreatic cancer

Lab requirements

Blood counts

no serious abnormalities

Kidney function

no serious abnormalities

Liver function

no serious abnormalities

Cardiac function

no serious abnormalities

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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