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OncoMatch/Clinical Trials/NCT06752746

A Study of Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of 9MW3011 in Patients With Polycythemia Vera

Is NCT06752746 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies 9MW3011 for polycythemia vera.

Phase 1RecruitingMabwell (Shanghai) Bioscience Co., Ltd.NCT06752746Data as of May 2026

Treatment: 9MW3011The goal of this clinical trial is to assess the safety, tolerability, pharmacokinetics, pharmacodynamics and immunogenicity of 9MW3011 in Chinese patients with Polycythemia Vera(PV).

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Extracted eligibility criteria

Cancer type

Myeloproliferative Neoplasm

Prior therapy

Must have received: hydroxyurea (hydroxyurea) — resistant or intolerant

resistant to or intolerant of hydroxyurea

Must have received: Interferon alpha (Interferon alpha) — resistant or intolerant

resistant to or intolerant of Interferon alpha

Cannot have received: monoclonal antibody

Subjects who have used monoclonal antibodies within the 6 months prior to screening

Cannot have received: antitumor therapeutic drugs for PV

Subjects who have received other antitumor therapeutic drugs for PV prior to screening

Lab requirements

Blood counts

Hematological indicators do not meet the requirements at the time of screening [excluded]

Hematological indicators do not meet the requirements at the time of screening. Abnormal QTc interval of electrocardiogram within the 6 months prior to screening.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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