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OncoMatch/Clinical Trials/NCT06740019

A Phase Ib Study of JMKX000197 Injection in the Treatment of Malignant Pleural Effusion

Is NCT06740019 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1 trial studies JMKX000197 for malignant pleural effusions (mpe).

Phase 1RecruitingJemincareNCT06740019Data as of Jun 2026Location: China

Treatment: JMKX000197A Phase Ib Study to Evaluate the Safety, Tolerance, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of JMKX000197 Injection in the Treatment of Malignant Pleural Effusion

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Extracted eligibility criteria

Treatments studied

Other

JMKX000197

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Demographics

Ages ≤ 75

Prior therapy

Cannot have received: STING agonist

Have used interferon gene stimulating factor (STING) agonists for pleural perfusion

Lab requirements

Blood counts

adequate organ function

Kidney function

adequate organ function

Liver function

adequate organ function

Adequate organ function.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06740019 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior STING agonist disqualifies patients from enrollment.

Is there an age limit?

Yes. Patients must be 75 years or younger.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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