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OncoMatch/Clinical Trials/NCT06727617

Serplulimab With Chemoradiotherapy for Postoperative Cervical Cancer With Risk Factors

Is NCT06727617 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies multiple treatments including Serplulimab and Chemotherapy for cervical cancers.

Phase 2RecruitingTianjin Medical University Cancer Institute and HospitalNCT06727617Data as of May 2026

Treatment: Serplulimab · ChemotherapyA Phase II Study of Serplulimab Plus Chemoradiotherapy as Adjuvant Treatment for Postoperative Cervical Cancer with Multiple Risk Factors

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Extracted eligibility criteria

Cancer type

Cervical Cancer

Biomarker criteria

Required: PD-L1 (CD274) cps ≥1 (cps ≥1)

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Must have received: surgery

Have undergone radical hysterectomy (Piver classification) and pelvic lymphadenectomy of type II or III

Cannot have received: pelvic radiotherapy

Patients who have previously received pelvic radiotherapy

Lab requirements

Blood counts

absolute neutrophil count of at least 1.5 × 10⁹/l; platelet count of at least 100 × 10⁹/l

Kidney function

creatinine levels not exceeding the upper limit of normal

Liver function

total bilirubin, alt, and ast levels not exceeding 1.5 times the upper limit of normal

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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