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OncoMatch/Clinical Trials/NCT06717711

Low-Intensity Extracorporeal Shockwave Therapy on Penile Rehabilitation After Robot-assisted Surgical Treatment of Genitourinary Cancers

Is NCT06717711 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies multiple treatments including Low-intensity Extracorporeal Shock Wave Therapy (LiESWT) and PDE5 inhibitor (tadalafil) for prostate carcinoma.

Phase 3RecruitingRegina Elena Cancer InstituteNCT06717711Data as of May 2026

Treatment: Low-intensity Extracorporeal Shock Wave Therapy (LiESWT) · PDE5 inhibitor (tadalafil)This prospective randomized controlled trial (RCT) is designed to provide high level evidence on the efficacy of Low-intensity Extracorporeal Shock Wave Therapy (Li-ESWT) in the treatment of post-Robot-Assisted (RA) Radical Prostatectomy (RP) erectile dysfunction (ED) in addition to PDE5 inhibitors (PDE5i) versus PDE5i alone. Our hypothesis is that early andrological rehabilitation that combines Li-ESWT and PDE5i could lead to faster and better recovery of valid erections for intercourse, with a greater rate of postoperative International Index of Erectile Function-5 (IIEF-5) compared to patients receiving PDE5i alone.

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Extracted eligibility criteria

Cancer type

Prostate Cancer

Disease stage

Grade: ISUP grade ≤2 (ISUP)

Prostate Cancer ISUP grade ≤2 and cT≤2 at prostate biopsy; Prostate Cancer ISUP grade ≤2 pT<3b and at final pathology

Prior therapy

Must have received: robot-assisted radical prostatectomy (nerve sparing RARP)

undergoing nerve sparing RARP

Cannot have received: pelvic radiotherapy

patients submitted to pelvic radiotherapy

Cannot have received: androgen deprivation

patients submitted to...androgen deprivation

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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