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OncoMatch/Clinical Trials/NCT06714383

Trilaciclib Combing Chemotherapy in the Neoadjuvant Treatment of Osteosarcoma

Is NCT06714383 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies multiple treatments including Trilaciclib and Pirarubicin for osteosarcoma.

Phase 2RecruitingPeking University People's HospitalNCT06714383Data as of Jun 2026Location: China

Treatment: Trilaciclib · Pirarubicin · LobaplatinTo evaluate the clinical application value in bone marrow protection of Trilaciclib in the neoadjuvant treatment of stage II/III classic osteosarcoma in combination with pirarubicin and lobaplatin.

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Extracted eligibility criteria

Treatments studied

Targeted therapy

Trilaciclib

Chemotherapy

Lobaplatin

Other

Pirarubicin

Cancer type

Osteosarcoma

Disease stage

Required: Stage Ⅱ, Ⅲ (Enneking)

Grade: high grade

Newly diagnosed stage Ⅱ-Ⅲ based on Enneking staging criteria

Performance status

ECOG 0–1(Restricted strenuous activity)

Demographics

Ages 14–70

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Lab requirements

Blood counts

Kidney function

Liver function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06714383 currently recruiting?

Yes, this trial is currently recruiting patients.

Can patients have received prior systemic therapy?

No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.

What disease stage is eligible?

Stage Ⅱ or Ⅲ is required.

Is there an age limit?

Yes. Patients must be 70 years or younger and at least 14 years old.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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Related pages

Osteosarcoma trials