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OncoMatch/Clinical Trials/NCT06713837

IMPACT-AML: A Randomized Pragmatic Clinical Trial for Relapsed or Refractory Acute Myeloid Leukemia.

Is NCT06713837 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies multiple treatments including High intensity therapies and Low intensity therapies for acute myeloid leukemia.

Phase 3RecruitingIstituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCSNCT06713837Data as of May 2026

Treatment: High intensity therapies · Low intensity therapiesThis is a multicenter, randomized, open-label, pragmatic low intervention clinical trial comparing high intensity reinduction chemotherapy with low intensity therapies in 1st or 2nd relapse Acute Myeloid Leukemia. The study is funded by European Commission (HORIZON-MISS-2022-CANCER-01-03, Project ID 101104421)

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Extracted eligibility criteria

Cancer type

Acute Myeloid Leukemia

Disease stage

Required: Stage RELAPSED, REFRACTORY (European leukemia Network (ELN) 2022)

1st or 2nd relapse or refractory according to European leukemia Network (ELN) 2022

Performance status

ECOG 0–3(Limited self-care)

Prior therapy

Cannot have received: investigational agent

Participation in another clinical trial with any investigational agents within 14 days or 5 drug half-lives (whatever comes first) prior to randomization

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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