OncoMatch/Clinical Trials/NCT06708663
HX009+ IN10018 with or Without Standard Chemotherapy for Advanced Solid Tumours
Is NCT06708663 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies HX009+IN10018 for biliary tract cancer.
Treatment: HX009+IN10018 — Phase IIa study of HX009+ IN10018 in combination with or without standard chemotherapy in patients with advanced solid tumours including biliary tract malignancies and malignant melanoma
Check if I qualifyExtracted eligibility criteria
Cancer type
Cholangiocarcinoma
Melanoma
Biomarker criteria
Excluded: BRAF v600e
Excluded: BRAF v600e
Excluded: FGFR2 fusion
Excluded: IDH1 mutation
Excluded: KRAS mutation
Excluded: NRAS mutation
Excluded: NTRK1 fusion
Excluded: NTRK2 fusion
Excluded: NTRK3 fusion
Excluded: RET fusion
Disease stage
Metastatic disease required
Performance status
ECOG 0–1(Restricted strenuous activity)
Lab requirements
Cardiac function
No severe cardiovascular disease such as symptomatic congestive heart failure (NYHA Class III or IV), unstable angina, uncontrolled hypertension (systolic blood pressure ≥160 and/or diastolic blood pressure ≥100 mmHg under pharmacological control), cardiac arrhythmia, history of myocardial infarction within 6 months, or history of arterial thromboembolism or pulmonary embolism within 3 months prior to the first administration of the drug
have severe cardiovascular disease such as symptomatic congestive heart failure (New York Heart Association Class III or IV), unstable angina, uncontrolled hypertension (systolic blood pressure ≥160 and/or diastolic blood pressure ≥100 mmHg under pharmacological control), cardiac arrhythmia, history of myocardial infarction within 6 months, or history of arterial thromboembolism or pulmonary embolism within 3 months prior to the first administration of the drug
Structured fields extracted by AI. May contain errors — verify against the official protocol.
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