OncoMatch/Clinical Trials/NCT06693323
Single-Center Eval of Clinical & Radiological Benefit AHCC in Combo W/ SOC Tx for HPV+ Pts W/ HNSCC
Is NCT06693323 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies AHCC®capsules for hnscc.
Treatment: AHCC®capsules — This is a phase 2, single-arm, open-label clinical trial determining safety and tolerability of AHCC in subjects with HPV-positive patients with Head and Neck Squamous Cell Carcinoma. These are subjects who have undergone surgery or will be undergoing surgery.
Check if I qualifyExtracted eligibility criteria
Treatments studied
Other
Cancer type
Head and Neck Squamous Cell Carcinoma
Biomarker criteria
Required: HPV positive
diagnosis of pathologically or cytologically proven HPV positive HNSCC
Performance status
ECOG 0–1(Restricted strenuous activity)
Demographics
Lab requirements
Blood counts
Absolute neutrophil count (ANC) ≥ 1,500/μL; Platelets ≥ 100,000/μL
Kidney function
Creatinine clearance > 30 mL/min using the Cockcroft-Gault formula
Liver function
Total bilirubin ≤ 1.5 × institutional upper limit of normal (ULN); AST or /ALT ≤ 3.0 × institutional ULN
Has adequate organ and marrow function as defined below, based on clinical laboratory assessments obtained ≤ 28 days prior to registration: 1. Absolute neutrophil count (ANC) ≥ 1,500/μL 2. Platelets ≥ 100,000/μL 3. Total bilirubin ≤ 1.5 × institutional upper limit of normal (ULN) 4. AST or /ALT ≤ 3.0 × institutional ULN 5. Creatinine clearance > 30 mL/min using the Cockcroft-Gault formula
Structured fields extracted by AI. May contain errors — verify against the official protocol.
US trial sites
- Chao Family Comprehensive Cancer Center, University of California, Irvine · Orange, California
Showing up to 5 US sites.
See all sites on ClinicalTrials.gov →Frequently asked questions
Is NCT06693323 currently recruiting?
Yes, this trial is currently recruiting patients.
Does this trial require HPV?
Yes, HPV positive is a required biomarker for enrollment.
Is there an age limit?
Yes. Patients must be 79 years or younger.
Could you qualify for this trial?
Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.
Check if I qualifyRelated pages