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OncoMatch/Clinical Trials/NCT06692166

A Study to Evaluate 9MW2821 Versus Treatment of Physician's Choice for Subjects With Recurrent or Metastatic Cervical Cancer

Is NCT06692166 recruiting? Yes, currently enrolling (Jun 2026). This Phase 3 trial studies multiple treatments including 9MW2821 and Chemotherapy for cervical cancer.

Phase 3RecruitingMabwell (Shanghai) Bioscience Co., Ltd.NCT06692166Data as of Jun 2026Location: China

Treatment: 9MW2821 · ChemotherapyThe purpose of this study is to compare the efficacy and safety of 9MW2821 and chemotherapy in participants with recurrent or metastatic cervical cancer who progressed on or after platinum-based chemotherapy.

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Extracted eligibility criteria

Treatments studied

Other

9MW2821Chemotherapy

Cancer type

Cervical Cancer

Disease stage

Metastatic disease required

Performance status

ECOG 0–1(Restricted strenuous activity)

Demographics

Ages ≤ 75
Female only

Prior therapy

Max 2 prior lines
Min 1 prior line

Must have received: platinum-based chemotherapy

Subject must have received a platinum-based chemotherapy with or without bevacizumab and received no more than 2 prior systemic therapy in the metastatic/recurrent setting. Subject must have experienced radiographic progression during or after the last treatment regimen.

Cannot have received: nectin-4 targeted antibody-drug conjugate

received treatment of nectin-4 targeted ADC

Cannot have received: antibody-drug conjugate with MMAE payload

received treatment of ADC with MMAE payload

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06692166 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior nectin-4 targeted antibody-drug conjugate, antibody-drug conjugate with MMAE payload disqualifies patients from enrollment.

Is there an age limit?

Yes. Patients must be 75 years or younger.

Is this trial open to male patients?

No. This trial enrolls female patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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