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OncoMatch/Clinical Trials/NCT06692166

A Study to Evaluate 9MW2821 Versus Treatment of Physician's Choice for Subjects With Recurrent or Metastatic Cervical Cancer

Is NCT06692166 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies multiple treatments including 9MW2821 and Chemotherapy for cervical cancer.

Phase 3RecruitingMabwell (Shanghai) Bioscience Co., Ltd.NCT06692166Data as of May 2026

Treatment: 9MW2821 · ChemotherapyThe purpose of this study is to compare the efficacy and safety of 9MW2821 and chemotherapy in participants with recurrent or metastatic cervical cancer who progressed on or after platinum-based chemotherapy.

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Extracted eligibility criteria

Cancer type

Cervical Cancer

Disease stage

Metastatic disease required

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Max 2 prior lines
Min 1 prior line

Must have received: platinum-based chemotherapy

Subject must have received a platinum-based chemotherapy with or without bevacizumab and received no more than 2 prior systemic therapy in the metastatic/recurrent setting. Subject must have experienced radiographic progression during or after the last treatment regimen.

Cannot have received: nectin-4 targeted antibody-drug conjugate

received treatment of nectin-4 targeted ADC

Cannot have received: antibody-drug conjugate with MMAE payload

received treatment of ADC with MMAE payload

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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