OncoMatch/Clinical Trials/NCT06686576
A Study of Neoadjuvant QL1706 in Participants With Untreated dMMR/MSI-H Resectable Colon Cancer
Is NCT06686576 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies multiple treatments including QL1706 and CAPEOX/Capecitabine for colon cancer.
Treatment: QL1706 · CAPEOX/Capecitabine — The goal of this clinical trial is to evaluate the efficacy of neoadjuvant QL1706 in participants with untreated T4N0 or Stage III (resectable), microsatellite instability high/ defective mismatch repair (MSI-H/dMMR) colon cancer
Check if I qualifyExtracted eligibility criteria
Cancer type
Colorectal Cancer
Disease stage
Required: Stage IIB, III (AJCC Stage VIII)
Excluded: Stage DISTANT METASTATIC DISEASE
Radiographic assessment showed a resectable stage IIB-III based on AJCC Stage VIII (cT4 or cN+ only). Has distant metastatic disease [excluded].
Performance status
ECOG 0–1(Restricted strenuous activity)
Prior therapy
Cannot have received: any antitumor therapy
Lab requirements
Blood counts
Adequate organ function as described in the protocol
Kidney function
Adequate organ function as described in the protocol
Liver function
Adequate organ function as described in the protocol
Adequate organ function as described in the protocol
Structured fields extracted by AI. May contain errors — verify against the official protocol.
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