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OncoMatch/Clinical Trials/NCT06679985

A Trial of Casdozokitug in Combination With Toripalimab Plus Bevacizumab in Participants With Unresectable and/or Locally Advanced or Metastatic Hepatocellular Carcinoma

Is NCT06679985 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies multiple treatments including Casdozokitug and Toripalimab for hepatocellular carcinoma.

Phase 2RecruitingCoherus Oncology, Inc.NCT06679985Data as of May 2026

Treatment: Casdozokitug · Toripalimab · BevacizumabThe main goals of this study are to evaluate the safety and efficacy of casdozokitug in combination with toripalimab plus bevacizumab and to define a recommended dose for casdozokitug in combination with toripalimab plus bevacizumab.

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Extracted eligibility criteria

Cancer type

Hepatocellular Carcinoma

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: systemic therapy

Cannot have received: anti-il-27 antibody or anti-il-27-targeted therapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Mayo Clinic - Scottsdale · Scottsdale, Arizona
  • University of Arizona - Cancer Center · Tucson, Arizona
  • Beverly Hills Cancer Center · Beverly Hills, California
  • City of Hope · Duarte, California
  • City of Hope at Irvine Lennar · Irvine, California

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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