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OncoMatch/Clinical Trials/NCT06673017

PTM-101 in Pancreatic Ductal Adenocarcinoma (PDAC)

Is NCT06673017 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1 trial studies PTM-101 for pancreatic ductal adenocarcinoma.

Phase 1RecruitingPanTher TherapeuticsNCT06673017Data as of Jun 2026

Treatment: PTM-101This is a multi-center, non-randomized, single-arm, open-label, phase Ib, dose escalation/dose expansion study of PTM-101 when combined with neoadjuvant chemotherapy for the treatment of treatment-naïve subjects with borderline resectable and locally advanced pancreatic ductal adenocarcinoma (PDAC).

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Extracted eligibility criteria

Treatments studied

Other

PTM-101

Cancer type

Pancreatic Cancer

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: chemotherapy

No prior chemo-, radio-, or surgical therapy for PDAC

Cannot have received: radiation therapy

No prior chemo-, radio-, or surgical therapy for PDAC

Cannot have received: surgery

No prior chemo-, radio-, or surgical therapy for PDAC

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Hoag Memorial Hospital Presbyterian · Newport Beach, California
  • Karmanos Cancer Institute · Detroit, Michigan
  • Northwell Health Zuckerberg Cancer Center · Lake Success, New York
  • University of Texas Southwestern Medical Center · Dallas, Texas
  • The University of Texas MD Anderson Cancer Center · Houston, Texas

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT06673017 currently recruiting?

Yes, this trial is currently recruiting patients.

Can patients have received prior systemic therapy?

No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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