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OncoMatch/Clinical Trials/NCT06667908

A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)

Is NCT06667908 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies multiple treatments including Durvalumab and JNJ-90301900 for carcinoma, non-small-cell lung.

Phase 2RecruitingJohnson & Johnson Enterprise Innovation Inc.NCT06667908Data as of Jun 2026Location: International · 10 countries

Treatment: JNJ-90301900 · Durvalumab · Concurrent Chemo/Radiation Therapy (cCRT): Carboplatin · Concurrent Chemo/Radiation Therapy (cCRT): PaclitaxelThe purpose of this study is to determine whether JNJ-90301900 added to concurrent platinum-based doublet chemotherapy with radiation therapy (cCRT) followed by consolidation immunotherapy (cIT) can improve objective response rate (ORR; that is percentage of participants whose best response is complete response or partial response during the study) in participants with locally advanced and unresectable stage III non-small cell lung cancer.

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Extracted eligibility criteria

Treatments studied

Immunotherapy

Durvalumab

Chemotherapy

Concurrent Chemo/Radiation Therapy (cCRT): CarboplatinConcurrent Chemo/Radiation Therapy (cCRT): Paclitaxel

Other

JNJ-90301900

Cancer type

Non-Small Cell Lung Carcinoma

Disease stage

Required: Stage III

Performance status

ECOG 0–1(Restricted strenuous activity)

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • University of Connecticut Health Center · Farmington, Connecticut
  • Yale University · New Haven, Connecticut
  • University of Miami · Miami, Florida
  • Orlando Health Cancer Institute · Orlando, Florida
  • Emory University Winship Cancer Institute · Atlanta, Georgia

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Frequently asked questions

Is NCT06667908 currently recruiting?

Yes, this trial is currently recruiting patients.

What disease stage is eligible?

Stage III is required.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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