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OncoMatch/Clinical Trials/NCT06664411

Pola-ZR2P in Previously Untreated DLBCL

Is NCT06664411 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies Polatuzumab Vedotin, Zanubrutinib, Rituximab, Lenalidomide and Prednisone as Induction Therapy for diffuse large b-cell lymphoma.

Phase 2RecruitingNavy General Hospital, BeijingNCT06664411Data as of Jun 2026Location: China

Treatment: Polatuzumab Vedotin, Zanubrutinib, Rituximab, Lenalidomide and Prednisone as Induction TherapyThe goal of this phase 2 trial is to test the safety and efficacy of Pola-ZR2P as induction therapy in patients with DLBCL.

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Extracted eligibility criteria

Treatments studied

Targeted therapy

Polatuzumab Vedotin, Zanubrutinib, Rituximab, Lenalidomide and Prednisone as Induction Therapy

Cancer type

Diffuse Large B-Cell Lymphoma

Non-Hodgkin Lymphoma

Demographics

Ages ≥ 14

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: chemotherapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06664411 currently recruiting?

Yes, this trial is currently recruiting patients.

Can patients have received prior systemic therapy?

No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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