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OncoMatch/Clinical Trials/NCT06641791

Palliative Steroeotactic Body Radiotherapy vs Palliative Standard Radiotherapy in Patients With Advanced Head and Neck Cancer

Is NCT06641791 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies non-drug interventions for advanced head and neck cancer.

Phase 3RecruitingCanadian Cancer Trials GroupNCT06641791Data as of May 2026

This study is being done to answer the following question: Does stereotactic body radiation therapy (SBRT) provide better cancer control compared to standard radiation therapy (RT) for those with advanced head and neck cancer?

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Extracted eligibility criteria

Cancer type

Head and Neck Squamous Cell Carcinoma

Disease stage

Required: Stage TX, T0-T4, N0-N3

Stages TX or T0-T4/N0-N3

Performance status

ECOG 0–3(Limited self-care)

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: systemic therapy (including immunotherapy)

Prior systemic therapy (including immunotherapy)

Cannot have received: radiotherapy to the head and neck

Exception: excluding superficial radiotherapy for head and neck skin cancer that does not overlap with current protocol treatment

Prior radiotherapy to the head and neck excluding superficial radiotherapy for head and neck skin cancer that does not overlap with current protocol treatment

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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